What is the aim of the systematic literature review?
The nAMD Barometer Leadership Coalition conducted a systematic literature review of factors affecting non-adherence to and non-persistence with intravitreal anti-VEGF therapy for nAMD, with the aims of:
- Identifying risk factors for non-adherence and non-persistence
- Evaluating existing strategies to improve adherence or persistence
- Investigating rates of non-adherence to and non-persistence with anti-VEGF therapy for nAMD in real-world practice
![Injection icon Injection icon](/sites/g/files/vrxlpx27766/files/2021-02/Icon1%402x.png)
Definitions for NA/NP are not standardised in nAMD
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Standardised definitions are needed to accurately investigate levels of NA/NP in the real-world
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Few studies have investigated the reasons for NA/NP
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There is a need to better understand risk factors associated with NA/NP
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NA/NP predominantly occurs within 12–24 months
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Represents a key window for patient education intervention
![Elderly icon Elderly icon](/sites/g/files/vrxlpx27766/files/2021-02/Icon4%402x.png)
Older age and lower income are common characteristics associated with NA/NP
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Triaging patients based on known risk factors for interventions should be explored
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Perception of stable disease is a key reason for NA/NP
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Represents an opportunity to improve patient education around the purpose of treatment to set appropriate expectations